Microfibrils

"Microfibrils" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Components of the extracellular matrix consisting primarily of fibrillin. They are essential for the integrity of elastic fibers.

Descriptor ID

D020894

MeSH Number(s)

A11.284.295.310.560

Concept/Terms

Microfibrils

Below are MeSH descriptors whose meaning is more general than "Microfibrils".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Extracellular Space [A11.284.295]
Extracellular Matrix [A11.284.295.310]
Microfibrils [A11.284.295.310.560]

Below are MeSH descriptors whose meaning is related to "Microfibrils".

Below are MeSH descriptors whose meaning is more specific than "Microfibrils".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Microfibrils" by people in Harvard Catalyst Profiles by year, and whether "Microfibrils" was a major or minor topic of these publication.

Bar chart showing 10 publications over 7 distinct years, with a maximum of 2 publications in 2013 and 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2004	1	0	1
2013	1	1	2
2016	0	2	2
2017	1	0	1
2018	0	1	1
2020	0	2	2

Below are the most recent publications written about "Microfibrils" by people in Profiles.

Latent-transforming growth factor beta-binding protein-2 (LTBP-2) is required for longevity but not for development of zonular fibers. Matrix Biol. 2021 01; 95:15-31.

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A positively selected FBN1 missense variant reduces height in Peruvian individuals. Nature. 2020 06; 582(7811):234-239.

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The Fibrillin-1 RGD Integrin Binding Site Regulates Gene Expression and Cell Function through microRNAs. J Mol Biol. 2019 01 18; 431(2):401-421.

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Fibrillins. Methods Cell Biol. 2018; 143:223-246.

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Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip. Biomaterials. 2016 12; 110:45-59.

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Characterization of metabolic health in mouse models of fibrillin-1 perturbation. Matrix Biol. 2016 09; 55:63-76.

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Latent TGF-ß binding protein-2 is essential for the development of ciliary zonule microfibrils. Hum Mol Genet. 2014 Nov 01; 23(21):5672-82.

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Tissue specific specialization of the nanoscale architecture of Arabidopsis. J Struct Biol. 2013 Nov; 184(2):103-14.

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Insight into the degradation of type-I collagen fibrils by MMP-8. J Mol Biol. 2013 May 27; 425(10):1815-25.

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Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment. Genesis. 2012 Aug; 50(8):635-41.

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