Harvard Catalyst Profiles

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Mice, Inbred CFTR

"Mice, Inbred CFTR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.


This graph shows the total number of publications written about "Mice, Inbred CFTR" by people in Harvard Catalyst Profiles by year, and whether "Mice, Inbred CFTR" was a major or minor topic of these publication.
Bar chart showing 13 publications over 10 distinct years, with a maximum of 2 publications in 2006 and 2010 and 2016
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.