Methylmalonate-Semialdehyde Dehydrogenase (Acylating)
"Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the VALINE; LEUCINE; and ISOLEUCINE catabolic pathways by catalyzing the oxidation of 2-methyl-3-oxopropanate to propanoyl-CoA using NAD+ as a coenzyme. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated BETA-ALANINE and 3-hydropropionic acid.
Below are MeSH descriptors whose meaning is more general than "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)".
Below are MeSH descriptors whose meaning is more specific than "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)".
This graph shows the total number of publications written about "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" by people in Harvard Catalyst Profiles by year, and whether "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
Below are the most recent publications written about "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" by people in Profiles.
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The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. Antimicrob Agents Chemother. 2010 Nov; 54(11):4626-35.
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Combined malonic, methylmalonic and ethylmalonic acid semialdehyde dehydrogenase deficiencies: an inborn error of beta-alanine, L-valine and L-alloisoleucine metabolism? J Inherit Metab Dis. 1993; 16(3):563-7.