Methylmalonate-Semialdehyde Dehydrogenase (Acylating)
"Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the VALINE; LEUCINE; and ISOLEUCINE catabolic pathways by catalyzing the oxidation of 2-methyl-3-oxopropanate to propanoyl-CoA using NAD+ as a coenzyme. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated BETA-ALANINE and 3-hydropropionic acid.
Below are MeSH descriptors whose meaning is more general than "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)".
Below are MeSH descriptors whose meaning is more specific than "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)".
This graph shows the total number of publications written about "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" by people in Harvard Catalyst Profiles by year, and whether "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
Below are the most recent publications written about "Methylmalonate-Semialdehyde Dehydrogenase (Acylating)" by people in Profiles.
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Su HC, Ramkissoon K, Doolittle J, Clark M, Khatun J, Secrest A, Wolfgang MC, Giddings MC. The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins. Antimicrob Agents Chemother. 2010 Nov; 54(11):4626-35.
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Gibson KM, Lee CF, Bennett MJ, Holmes B, Nyhan WL. Combined malonic, methylmalonic and ethylmalonic acid semialdehyde dehydrogenase deficiencies: an inborn error of beta-alanine, L-valine and L-alloisoleucine metabolism? J Inherit Metab Dis. 1993; 16(3):563-7.