"Megestrol Acetate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Concept/Terms
Borea- Borea
- Madaus Brand of Megestrol Acetate
Lin-Megestrol- Lin-Megestrol
- Lin Megestrol
- LinMegestrol
- Linson Pharma Brand of Megestrol Acetate
Maygace- Maygace
- Bristol-Myers Brand of Megestrol Acetate
- Bristol Myers Brand of Megestrol Acetate
Megefren- Megefren
- Prasfarma Brand of Megestrol Acetate
Mestrel- Mestrel
- Lemery Brand of Megestrol Acetate
Nu-Megestrol- Nu-Megestrol
- Nu Megestrol
- NuMegestrol
- Nu-Pharm Brand of Megestrol Acetate
- Nu Pharm Brand of Megestrol Acetate
Apo-Megestrol- Apo-Megestrol
- Apo Megestrol
- ApoMegestrol
- Apotex Brand of Megestrol Acetate
Megace- Megace
- Squibb Brand of Megestrol Acetate
- Megostat
- Bristol-Myers Squibb Brand of Megestrol Acetate
- Bristol Myers Squibb Brand of Megestrol Acetate
- Megestat
Below are MeSH descriptors whose meaning is more general than "Megestrol Acetate".
Below are MeSH descriptors whose meaning is more specific than "Megestrol Acetate".
This graph shows the total number of publications written about "Megestrol Acetate" by people in Harvard Catalyst Profiles by year, and whether "Megestrol Acetate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
Below are the most recent publications written about "Megestrol Acetate" by people in Profiles.
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Metabolism of megestrol acetate in vitro and the role of oxidative metabolites. Xenobiotica. 2018 Oct; 48(10):973-983.
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Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study. Gynecol Oncol. 2016 Apr; 141(1):43-8.
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Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial. Ann Oncol. 2014 Apr; 25(4):831-836.
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Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system. PLoS One. 2013; 8(8):e72148.
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Meningioma-toward an improved understanding of the role of sex steroids in tumor development and progression. World Neurosurg. 2011 Nov; 76(5):409-11.
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Megestrol acetate inhibits the expression of cytoplasmic aromatase through nuclear C/EBPß in reperfusion injury-induced ischemic rat hippocampus. Eur J Pharmacol. 2011 Mar 11; 654(3):217-25.
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Oral metronomic chemo-hormonal-therapy of metastatic breast cancer with cyclophosphamide and megestrol acetate. J Chemother. 2010 Jun; 22(3):201-4.
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Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients. Clin Nutr. 2006 Oct; 25(5):711-5.
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Enthusiasm lacks data for megestrol acetate. J Am Geriatr Soc. 2006 Mar; 54(3):548; author reply 548-9.
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Cannonball metastases with favourable prognosis. Ir J Med Sci. 2005 Jan-Mar; 174(1):61-4.