"Medical Futility" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)
Concept/Terms
Futile Treatment- Futile Treatment
- Futile Treatments
- Treatment, Futile
- Treatments, Futile
Below are MeSH descriptors whose meaning is more general than "Medical Futility".
Below are MeSH descriptors whose meaning is more specific than "Medical Futility".
This graph shows the total number of publications written about "Medical Futility" by people in Harvard Catalyst Profiles by year, and whether "Medical Futility" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1995 | 3 | 1 | 4 |
| 1996 | 2 | 1 | 3 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 3 | 4 |
| 2001 | 1 | 3 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 3 | 5 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 2 | 4 |
| 2007 | 3 | 0 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 4 | 2 | 6 |
| 2011 | 0 | 2 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 3 | 6 |
| 2015 | 5 | 0 | 5 |
| 2016 | 1 | 3 | 4 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 4 | 6 |
| 2019 | 3 | 3 | 6 |
| 2020 | 4 | 1 | 5 |
| 2021 | 1 | 5 | 6 |
| 2022 | 2 | 2 | 4 |
Below are the most recent publications written about "Medical Futility" by people in Profiles.
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Mass casualty CPR: Flawed, futile or a first responder mandate? Resuscitation. 2022 12; 181:132.
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Role of Transfusion Volume and Transfusion Rate as Markers of Futility During Ultramassive Blood Transfusion in Trauma. J Am Coll Surg. 2022 09 01; 235(3):468-480.
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Bayesian and frequentist approaches to sequential monitoring for futility in oncology basket trials: A comparison of Simon's two-stage design and Bayesian predictive probability monitoring with information sharing across baskets. PLoS One. 2022; 17(8):e0272367.
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Effect of Deferoxamine on Trajectory of Recovery After Intracerebral Hemorrhage: A Post Hoc Analysis of the i-DEF Trial. Stroke. 2022 07; 53(7):2204-2210.
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The use of external control data for predictions and futility interim analyses in clinical trials. Neuro Oncol. 2022 02 01; 24(2):247-256.
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Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 02; 175(2):234-243.
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The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer - a study protocol. BMC Cancer. 2021 Nov 18; 21(1):1238.
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Massive transfusion and severe blood shortages: establishing and implementing predictors of futility. Br J Anaesth. 2022 02; 128(2):e71-e74.
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Questioning the Futility of Cardiopulmonary Resuscitation in Patients With Severe Coronavirus Disease 2019. Crit Care Med. 2021 08 01; 49(8):e795-e796.
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Evaluation of Aducanumab for Alzheimer Disease: Scientific Evidence and Regulatory Review Involving Efficacy, Safety, and Futility. JAMA. 2021 May 04; 325(17):1717-1718.