Mechanotransduction, Cellular
"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.
MeSH Number(s)
G01.154.100.440
G01.595.100.440
G02.111.087.800.580
G02.149.115.800.580
G04.299.880.580
Concept/Terms
Mechanotransduction, Cellular- Mechanotransduction, Cellular
- Signal Transduction, Mechanical
- Mechanical Signal Transduction
- Mechanosensory Transduction
- Transduction, Mechanosensory
- Cellular Mechanotransduction
Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".
Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".
This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in Harvard Catalyst Profiles by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2003 | 8 | 3 | 11 |
| 2004 | 13 | 1 | 14 |
| 2005 | 9 | 6 | 15 |
| 2006 | 9 | 4 | 13 |
| 2007 | 16 | 1 | 17 |
| 2008 | 8 | 5 | 13 |
| 2009 | 10 | 7 | 17 |
| 2010 | 12 | 2 | 14 |
| 2011 | 8 | 3 | 11 |
| 2012 | 13 | 8 | 21 |
| 2013 | 15 | 5 | 20 |
| 2014 | 21 | 6 | 27 |
| 2015 | 13 | 8 | 21 |
| 2016 | 6 | 12 | 18 |
| 2017 | 16 | 6 | 22 |
| 2018 | 16 | 5 | 21 |
| 2019 | 13 | 5 | 18 |
| 2020 | 10 | 13 | 23 |
| 2021 | 16 | 9 | 25 |
| 2022 | 4 | 4 | 8 |
| 2023 | 1 | 1 | 2 |
Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.
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From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics. Biochem J. 2023 02 27; 480(4):243-257.
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Dissecting Physical and Biochemical Effects in Nanotopographical Regulation of Cell Behavior. ACS Nano. 2023 02 14; 17(3):2124-2133.
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Piezo mechanosensory channels regulate centrosome integrity and mitotic entry. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213846120.
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Single-molecule characterization of subtype-specific ß1 integrin mechanics. Nat Commun. 2022 12 03; 13(1):7471.
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Mechanotransduction in the pathogenesis of non-alcoholic fatty liver disease. J Hepatol. 2022 12; 77(6):1642-1656.
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Dimensionality-Dependent Mechanical Stretch Regulation of Cell Behavior. ACS Appl Mater Interfaces. 2022 Apr 20; 14(15):17081-17092.
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Role of mechanosensitive channels/receptors in atherosclerosis. Am J Physiol Cell Physiol. 2022 05 01; 322(5):C927-C938.
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PIEZO1, sensing the touch during erythropoiesis. Curr Opin Hematol. 2022 05 01; 29(3):112-118.
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Hippo signalling in the liver: role in development, regeneration and disease. Nat Rev Gastroenterol Hepatol. 2022 05; 19(5):297-312.
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PIEZO1 mediates a mechanothrombotic pathway in diabetes. Sci Transl Med. 2022 01 05; 14(626):eabk1707.