Mazindol

"Mazindol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.

Descriptor ID

D008454

MeSH Number(s)

D03.438.513.500

Concept/Terms

Below are MeSH descriptors whose meaning is more general than "Mazindol".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 2-Ring [D03.438]
Isoindoles [D03.438.513]
Mazindol [D03.438.513.500]

Below are MeSH descriptors whose meaning is related to "Mazindol".

Below are MeSH descriptors whose meaning is more specific than "Mazindol".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mazindol" by people in Harvard Catalyst Profiles by year, and whether "Mazindol" was a major or minor topic of these publication.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 1994 and 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
1994	1	1	2
1998	0	1	1
2001	0	1	1
2002	0	2	2
2004	0	1	1

Below are the most recent publications written about "Mazindol" by people in Profiles.

Augood SJ, Hollingsworth Z, Albers DS, Yang L, Leung J, Breakefield XO, Standaert DG. Dopamine transmission in DYT1 dystonia. Adv Neurol. 2004; 94:53-60.

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Johnston T, Duty S. Changes in GABA(B) receptor mRNA expression in the rodent basal ganglia and thalamus following lesion of the nigrostriatal pathway. Neuroscience. 2003; 120(4):1027-35.

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Lin Z, Uhl GR. Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism. Mol Pharmacol. 2002 Apr; 61(4):885-91.

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Xu K, Xu YH, Chen JF, Schwarzschild MA. Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice. Neurosci Lett. 2002 Mar 29; 322(1):13-6.

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Dutta AK, Reith ME, Madras BK. Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter. Synapse. 2001 Feb; 39(2):175-81.

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Augood SJ, Hollingsworth ZR, Standaert DG, Emson PC, Penney JB. Localization of dopaminergic markers in the human subthalamic nucleus. J Comp Neurol. 2000 May 29; 421(2):247-55.

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Chadha A, Dawson LG, Jenner PG, Duty S. Effect of unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway on GABA(A) receptor subunit gene expression in the rodent basal ganglia and thalamus. Neuroscience. 2000; 95(1):119-26.

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Yang L, Matthews RT, Schulz JB, Klockgether T, Liao AW, Martinou JC, Penney JB, Hyman BT, Beal MF. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. J Neurosci. 1998 Oct 15; 18(20):8145-52.

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Madras BK, Kaufman MJ. Cocaine accumulates in dopamine-rich regions of primate brain after i.v. administration: comparison with mazindol distribution. Synapse. 1994 Nov; 18(3):261-75.

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Arregui A, Hollingsworth Z, Penney JB, Young AB. Autoradiographic evidence for increased dopamine uptake sites in striatum of hypoxic mice. Neurosci Lett. 1994 Feb 14; 167(1-2):195-7.

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