Harvard Catalyst Profiles

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Maturation-Promoting Factor

"Maturation-Promoting Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.


This graph shows the total number of publications written about "Maturation-Promoting Factor" by people in Harvard Catalyst Profiles by year, and whether "Maturation-Promoting Factor" was a major or minor topic of these publication.
Bar chart showing 13 publications over 9 distinct years, with a maximum of 4 publications in 1992
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.