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Mannose-Binding Protein-Associated Serine Proteases

"Mannose-Binding Protein-Associated Serine Proteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

This graph shows the total number of publications written about "Mannose-Binding Protein-Associated Serine Proteases" by people in Harvard Catalyst Profiles by year, and whether "Mannose-Binding Protein-Associated Serine Proteases" was a major or minor topic of these publication.
Bar chart showing 20 publications over 10 distinct years, with a maximum of 5 publications in 2011
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.