Mannose-Binding Protein-Associated Serine Proteases
"Mannose-Binding Protein-Associated Serine Proteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
MeSH Number(s)
D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
Concept/Terms
Mannose-Binding Protein-Associated Serine Proteases- Mannose-Binding Protein-Associated Serine Proteases
- Mannose-Binding Protein-Associated Serine Protease
- Mannose Binding Protein Associated Serine Protease
- MBP-Associated Serine Protease
- MBP Associated Serine Protease
- Serine Protease, MBP-Associated
- MASPs
- Mannan-Binding Lectin Serine Proteases
- Mannan Binding Lectin Serine Proteases
- MBL-Associated Serine Proteases
- MBL Associated Serine Proteases
- Serine Proteases, MBL-Associated
- MASP Proteases
- Proteases, MASP
MASP-Related Protein- MASP-Related Protein
- MASP Related Protein
- Protein, MASP-Related
- MBP-Associated Serine Protease-Related Protein
- MBP Associated Serine Protease Related Protein
Below are MeSH descriptors whose meaning is more general than "Mannose-Binding Protein-Associated Serine Proteases".
Below are MeSH descriptors whose meaning is more specific than "Mannose-Binding Protein-Associated Serine Proteases".
This graph shows the total number of publications written about "Mannose-Binding Protein-Associated Serine Proteases" by people in Harvard Catalyst Profiles by year, and whether "Mannose-Binding Protein-Associated Serine Proteases" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
| 2010 | 3 | 0 | 3 |
| 2011 | 4 | 0 | 4 |
| 2012 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
Below are the most recent publications written about "Mannose-Binding Protein-Associated Serine Proteases" by people in Profiles.
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Recruitment of Human C1 Esterase Inhibitor Controls Complement Activation on Blood Stage Plasmodium falciparum Merozoites. J Immunol. 2017 06 15; 198(12):4728-4737.
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Lectin-complement pathway molecules are decreased in patients with cirrhosis and constitute the risk of bacterial infections. Liver Int. 2017 07; 37(7):1023-1031.
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MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked. Sci Rep. 2016 08 18; 6:31877.
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Familial Recurrence of 3MC Syndrome in Consanguineous Families: A Clinical and Molecular Diagnostic Approach With Review of the Literature. Cleft Palate Craniofac J. 2017 11; 54(6):739-748.
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Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma. Environ Mol Mutagen. 2013 Jan; 54(1):72-7.
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Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis. Circulation. 2012 Oct 30; 126(18):2227-35.
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The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection. PLoS Pathog. 2012; 8(7):e1002793.
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MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children. Oral Dis. 2012 May; 18(4):389-95.
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Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis. J Immunol. 2012 Jan 15; 188(2):885-91.
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Mannose-binding lectin and the balance between immune protection and complication. Expert Rev Anti Infect Ther. 2011 Dec; 9(12):1179-90.