"Macrophage Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
Concept/Terms
Macrophage Activation- Macrophage Activation
- Activation, Macrophage
- Activations, Macrophage
- Macrophage Activations
Below are MeSH descriptors whose meaning is more general than "Macrophage Activation".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation".
This graph shows the total number of publications written about "Macrophage Activation" by people in Harvard Catalyst Profiles by year, and whether "Macrophage Activation" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 2 | 4 |
| 1992 | 2 | 5 | 7 |
| 1993 | 1 | 3 | 4 |
| 1994 | 0 | 4 | 4 |
| 1995 | 1 | 6 | 7 |
| 1996 | 2 | 4 | 6 |
| 1997 | 3 | 7 | 10 |
| 1998 | 0 | 3 | 3 |
| 1999 | 1 | 5 | 6 |
| 2000 | 4 | 5 | 9 |
| 2001 | 1 | 2 | 3 |
| 2002 | 6 | 5 | 11 |
| 2003 | 4 | 6 | 10 |
| 2004 | 2 | 12 | 14 |
| 2005 | 2 | 4 | 6 |
| 2006 | 2 | 7 | 9 |
| 2007 | 6 | 8 | 14 |
| 2008 | 3 | 5 | 8 |
| 2009 | 2 | 7 | 9 |
| 2010 | 1 | 11 | 12 |
| 2011 | 4 | 6 | 10 |
| 2012 | 5 | 8 | 13 |
| 2013 | 6 | 11 | 17 |
| 2014 | 7 | 12 | 19 |
| 2015 | 9 | 7 | 16 |
| 2016 | 11 | 11 | 22 |
| 2017 | 8 | 9 | 17 |
| 2018 | 8 | 9 | 17 |
| 2019 | 9 | 9 | 18 |
| 2020 | 6 | 13 | 19 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Macrophage Activation" by people in Profiles.
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Ergosta-7,9(11),22-trien-3ß-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation. Molecules. 2021 May 17; 26(10).
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Lipid Profile of Activated Macrophages and Contribution of Group V Phospholipase A2. Biomolecules. 2020 12 29; 11(1).
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The transition of M-CSF-derived human macrophages to a growth-promoting phenotype. Blood Adv. 2020 11 10; 4(21):5460-5472.
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Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation. Dev Cell. 2020 12 07; 55(5):617-628.e6.
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Thrombosis in COVID-19. Am J Hematol. 2020 12; 95(12):1578-1589.
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NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus. Arthritis Rheumatol. 2020 10; 72(10):1707-1720.
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Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis. Cell Rep. 2020 08 04; 32(5):107998.
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Improved prediction of mortality by combinations of inflammatory markers and standard clinical scores in patients with acute-on-chronic liver failure and acute decompensation. J Gastroenterol Hepatol. 2021 Jan; 36(1):240-248.
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Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation. J Neuroinflammation. 2020 Jun 19; 17(1):194.
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S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus. Arterioscler Thromb Vasc Biol. 2020 08; 40(8):1838-1853.