"Macrophage Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
Concept/Terms
Macrophage Activation- Macrophage Activation
- Activation, Macrophage
- Activations, Macrophage
- Macrophage Activations
Below are MeSH descriptors whose meaning is more general than "Macrophage Activation".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation".
This graph shows the total number of publications written about "Macrophage Activation" by people in Harvard Catalyst Profiles by year, and whether "Macrophage Activation" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 2 | 5 | 7 |
| 1993 | 1 | 3 | 4 |
| 1994 | 0 | 4 | 4 |
| 1995 | 0 | 6 | 6 |
| 1996 | 2 | 4 | 6 |
| 1997 | 3 | 7 | 10 |
| 1998 | 0 | 3 | 3 |
| 1999 | 1 | 5 | 6 |
| 2000 | 4 | 5 | 9 |
| 2001 | 1 | 2 | 3 |
| 2002 | 6 | 5 | 11 |
| 2003 | 4 | 6 | 10 |
| 2004 | 2 | 12 | 14 |
| 2005 | 2 | 4 | 6 |
| 2006 | 2 | 7 | 9 |
| 2007 | 6 | 8 | 14 |
| 2008 | 4 | 5 | 9 |
| 2009 | 2 | 6 | 8 |
| 2010 | 1 | 11 | 12 |
| 2011 | 4 | 6 | 10 |
| 2012 | 5 | 8 | 13 |
| 2013 | 6 | 11 | 17 |
| 2014 | 7 | 12 | 19 |
| 2015 | 8 | 8 | 16 |
| 2016 | 10 | 11 | 21 |
| 2017 | 8 | 9 | 17 |
| 2018 | 7 | 11 | 18 |
| 2019 | 9 | 8 | 17 |
| 2020 | 8 | 15 | 23 |
| 2021 | 5 | 4 | 9 |
| 2022 | 1 | 1 | 2 |
Below are the most recent publications written about "Macrophage Activation" by people in Profiles.
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Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
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SLAMF7 engagement superactivates macrophages in acute and chronic inflammation. Sci Immunol. 2022 02 11; 7(68):eabf2846.
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Macrophage-Mediated Immune Responses: From Fatty Acids to Oxylipins. Molecules. 2021 Dec 28; 27(1).
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Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. Cell Rep. 2021 11 02; 37(5):109955.
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Metabolic Adaptation of Macrophages as Mechanism of Defense against Crystalline Silica. J Immunol. 2021 09 15; 207(6):1627-1640.
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Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021 09 14; 54(9):2072-2088.e7.
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Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium. Stem Cell Reports. 2021 07 13; 16(7):1735-1748.
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Ergosta-7,9(11),22-trien-3ß-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation. Molecules. 2021 May 17; 26(10).
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Methylglyoxal Drives a Distinct, Nonclassical Macrophage Activation Status. Thromb Haemost. 2021 Nov; 121(11):1464-1475.
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The association of soluble CD163, a novel biomarker of macrophage activation, with type 2 diabetes mellitus and its underlying physiological disorders: A systematic review. Obes Rev. 2021 09; 22(9):e13257.