Lymphotoxin alpha1, beta2 Heterotrimer
"Lymphotoxin alpha1, beta2 Heterotrimer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.
MeSH Number(s)
D12.644.276.374.750.505
D12.644.276.972.505
D12.776.467.374.750.505
D12.776.467.972.505
D23.529.374.750.505
D23.529.972.505
Concept/Terms
Lymphotoxin alpha1, beta2 Heterotrimer- Lymphotoxin alpha1, beta2 Heterotrimer
- Lymphotoxin alphabeta
- Lymphotoxin alphabeta Heterotrimer
- Heterotrimer, Lymphotoxin alphabeta
- alphabeta Heterotrimer, Lymphotoxin
- Lymphotoxin alpha1beta2
- alpha1beta2, Lymphotoxin
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin alpha1, beta2 Heterotrimer".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin alpha1, beta2 Heterotrimer".
This graph shows the total number of publications written about "Lymphotoxin alpha1, beta2 Heterotrimer" by people in Harvard Catalyst Profiles by year, and whether "Lymphotoxin alpha1, beta2 Heterotrimer" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
Below are the most recent publications written about "Lymphotoxin alpha1, beta2 Heterotrimer" by people in Profiles.
-
CXCL13 responsiveness but not CXCR5 expression by late transitional B cells initiates splenic white pulp formation. J Immunol. 2015 Mar 15; 194(6):2616-23.
-
Lymphotoxin a1ß2 expression on B cells is required for follicular dendritic cell activation during the germinal center response. Eur J Immunol. 2013 Feb; 43(2):348-59.
-
B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity. 2012 Mar 23; 36(3):415-26.