 Lymphokines
"Lymphokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those involved in cellular immunity.
| Descriptor ID |
D008222
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| MeSH Number(s) |
D12.644.276.374.480 D12.776.467.374.480 D23.529.374.480
|
| Concept/Terms |
Lymphokines- Lymphokines
- Lymphocyte Mediators
- Mediators, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphokines".
Below are MeSH descriptors whose meaning is more specific than "Lymphokines".
This graph shows the total number of publications written about "Lymphokines" by people in Harvard Catalyst Profiles by year, and whether "Lymphokines" was a major or minor topic of these publication.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 4 | 2 | 6 | | 1981 | 6 | 3 | 9 | | 1982 | 11 | 3 | 14 | | 1983 | 9 | 6 | 15 | | 1984 | 12 | 11 | 23 | | 1985 | 17 | 11 | 28 | | 1986 | 14 | 7 | 21 | | 1987 | 14 | 8 | 22 | | 1988 | 13 | 9 | 22 | | 1989 | 3 | 10 | 13 | | 1990 | 6 | 7 | 13 | | 1991 | 10 | 4 | 14 | | 1992 | 11 | 4 | 15 | | 1993 | 9 | 3 | 12 | | 1994 | 12 | 6 | 18 | | 1995 | 30 | 4 | 34 | | 1996 | 41 | 9 | 50 | | 1997 | 31 | 18 | 49 | | 1998 | 29 | 17 | 46 | | 1999 | 26 | 18 | 44 | | 2000 | 31 | 21 | 52 | | 2001 | 56 | 26 | 82 | | 2002 | 38 | 43 | 81 | | 2003 | 22 | 24 | 46 | | 2005 | 1 | 0 | 1 | | 2007 | 2 | 1 | 3 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 3 | 4 | | 2011 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Lymphokines" by people in Profiles.
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Wu Q, Hou X, Xia J, Qian X, Miele L, Sarkar FH, Wang Z. Emerging roles of PDGF-D in EMT progression during tumorigenesis. Cancer Treat Rev. 2013 Oct; 39(6):640-6.
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Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clin Cancer Res. 2011 Jun 1; 17(11):3638-48.
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Schellens IM, Pogany K, Westerlaken GH, Borghans JA, Miedema F, van Valkengoed IG, Kroon FP, Lange JM, Brinkman K, Prins JM, van Baarle D. Immunological analysis of treatment interruption after early highly active antiretroviral therapy. Viral Immunol. 2010 Dec; 23(6):609-18.
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Yang SH, Park MJ, Yoon IH, Kim SY, Hong SH, Shin JY, Nam HY, Kim YH, Kim B, Park CG. Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10. Exp Mol Med. 2009 May 31; 41(5):315-24.
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Sprague AH, Khalil RA. Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol. 2009 Sep 15; 78(6):539-52.
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Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Trung TN, Bille C, Lidral AC, Murray JC. Genetic determinants of facial clefting: analysis of 357 candidate genes using two national cleft studies from Scandinavia. PLoS One. 2009; 4(4):e5385.
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McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, McCutcheon K, Milano R, Tam A, Lee DY, Lucien L, Brannigan BW, Ulkus LE, Ma XJ, Erlander MG, Haber DA, Sharma SV, Settleman J. Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors. Cancer Res. 2009 May 1; 69(9):3937-46.
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di Tomaso E, London N, Fuja D, Logie J, Tyrrell JA, Kamoun W, Munn LL, Jain RK. PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. PLoS One. 2009; 4(4):e5123.
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Cui J, Lei H, Samad A, Basavanthappa S, Maberley D, Matsubara J, Kazlauskas A. PDGF receptors are activated in human epiretinal membranes. Exp Eye Res. 2009 Mar; 88(3):438-44.
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Lei H, Velez G, Hovland P, Hirose T, Kazlauskas A. Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2008 Jan; 49(1):42-8.
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