Lymphocytes, Tumor-Infiltrating
"Lymphocytes, Tumor-Infiltrating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
MeSH Number(s)
A11.118.637.555.567.650
A15.145.229.637.555.567.650
A15.382.490.555.567.650
Concept/Terms
Lymphocytes, Tumor-Infiltrating- Lymphocytes, Tumor-Infiltrating
- Lymphocytes, Tumor Infiltrating
- Tumor-Infiltrating Lymphocytes
- Lymphocyte, Tumor-Infiltrating
- Tumor Infiltrating Lymphocytes
- Tumor-Infiltrating Lymphocyte
Tumor-Derived Activated Cells- Tumor-Derived Activated Cells
- Activated Cell, Tumor-Derived
- Activated Cells, Tumor-Derived
- Tumor Derived Activated Cells
- Tumor-Derived Activated Cell
Below are MeSH descriptors whose meaning is more general than "Lymphocytes, Tumor-Infiltrating".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytes, Tumor-Infiltrating".
This graph shows the total number of publications written about "Lymphocytes, Tumor-Infiltrating" by people in Harvard Catalyst Profiles by year, and whether "Lymphocytes, Tumor-Infiltrating" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 5 | 3 | 8 |
| 1994 | 3 | 1 | 4 |
| 1996 | 1 | 2 | 3 |
| 1997 | 4 | 0 | 4 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 3 | 4 |
| 2000 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 6 | 2 | 8 |
| 2007 | 7 | 0 | 7 |
| 2008 | 6 | 0 | 6 |
| 2009 | 3 | 4 | 7 |
| 2010 | 4 | 1 | 5 |
| 2011 | 3 | 4 | 7 |
| 2012 | 3 | 4 | 7 |
| 2013 | 6 | 4 | 10 |
| 2014 | 7 | 9 | 16 |
| 2015 | 13 | 5 | 18 |
| 2016 | 21 | 15 | 36 |
| 2017 | 19 | 22 | 41 |
| 2018 | 19 | 15 | 34 |
| 2019 | 24 | 28 | 52 |
| 2020 | 10 | 42 | 52 |
| 2021 | 24 | 32 | 56 |
| 2022 | 7 | 18 | 25 |
| 2023 | 0 | 2 | 2 |
Below are the most recent publications written about "Lymphocytes, Tumor-Infiltrating" by people in Profiles.
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Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies. JAMA Dermatol. 2023 02 01; 159(2):215-216.
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Association of Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes on Standard Histologic Images With Outcomes of Immunotherapy in Patients With NSCLC. JAMA Oncol. 2023 01 01; 9(1):51-60.
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Characterization of the tumor-infiltrating lymphocyte landscape in sinonasal mucosal melanoma. Pathol Res Pract. 2023 Jan; 241:154289.
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Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4+ T-cell Responses in Glioblastoma. Clin Cancer Res. 2022 12 15; 28(24):5368-5382.
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Longitudinal single-cell analysis of a patient receiving adoptive cell therapy reveals potential mechanisms of treatment failure. Mol Cancer. 2022 12 14; 21(1):219.
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Nociceptor neurons affect cancer immunosurveillance. Nature. 2022 Nov; 611(7935):405-412.
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Prognostic role of inflammatory diets in colorectal cancer overall and in strata of tumor-infiltrating lymphocyte levels. Clin Transl Med. 2022 11; 12(11):e1114.
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Coexisting Alterations of MHC Class I Antigen Presentation and IFN? Signaling Mediate Acquired Resistance of Melanoma to Post-PD-1 Immunotherapy. Cancer Immunol Res. 2022 10 04; 10(10):1254-1262.
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Tumor Immune Microenvironment Changes by Multiplex Immunofluorescence Staining in a Pilot Study of Neoadjuvant Talazoparib for Early-Stage Breast Cancer Patients with a Hereditary BRCA Mutation. Clin Cancer Res. 2022 09 01; 28(17):3669-3676.
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Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors. Cancer Immunol Res. 2022 08 03; 10(8):932-946.