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Lymphocyte Culture Test, Mixed

"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.


This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in Harvard Catalyst Profiles by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publication.
Bar chart showing 218 publications over 30 distinct years, with a maximum of 16 publications in 1996
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.