Luteinizing Hormone, beta Subunit
"Luteinizing Hormone, beta Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
MeSH Number(s)
D06.472.699.322.576.463.500
D06.472.699.631.525.343.463.500
D12.644.548.691.525.343.463.500
Concept/Terms
Luteinizing Hormone, beta Subunit- Luteinizing Hormone, beta Subunit
- LH, beta Subunit
- LH-beta
- LH beta
- Lutropin-beta
- Lutropin beta
- ICSH, beta Subunit
- Luteinizing Hormone, beta Chain
- Lutropin, beta Subunit
- Luteinizing Hormone, beta Polypeptide Chain
Below are MeSH descriptors whose meaning is more general than "Luteinizing Hormone, beta Subunit".
- Chemicals and Drugs [D]
- Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
- Peptide Hormones [D06.472.699]
- Gonadotropins [D06.472.699.322]
- Gonadotropins, Pituitary [D06.472.699.322.576]
- Luteinizing Hormone [D06.472.699.322.576.463]
- Luteinizing Hormone, beta Subunit [D06.472.699.322.576.463.500]
- Pituitary Hormones [D06.472.699.631]
- Pituitary Hormones, Anterior [D06.472.699.631.525]
- Gonadotropins, Pituitary [D06.472.699.631.525.343]
- Luteinizing Hormone [D06.472.699.631.525.343.463]
- Luteinizing Hormone, beta Subunit [D06.472.699.631.525.343.463.500]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Peptide Hormones [D12.644.548]
- Pituitary Hormones [D12.644.548.691]
- Pituitary Hormones, Anterior [D12.644.548.691.525]
- Gonadotropins, Pituitary [D12.644.548.691.525.343]
- Luteinizing Hormone [D12.644.548.691.525.343.463]
- Luteinizing Hormone, beta Subunit [D12.644.548.691.525.343.463.500]
Below are MeSH descriptors whose meaning is more specific than "Luteinizing Hormone, beta Subunit".
This graph shows the total number of publications written about "Luteinizing Hormone, beta Subunit" by people in Harvard Catalyst Profiles by year, and whether "Luteinizing Hormone, beta Subunit" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
Below are the most recent publications written about "Luteinizing Hormone, beta Subunit" by people in Profiles.
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Irisin stimulates gonadotropins gene expression in tilapia (Oreochromis niloticus) pituitary cells. Anim Reprod Sci. 2017 Oct; 185:140-147.
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Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency. J Biol Chem. 2017 06 09; 292(23):9815-9829.
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Production and characterization of monoclonal antibodies against recombinant tethered follicle-stimulating hormone from Japanese eel Anguilla japonica. Gen Comp Endocrinol. 2016 07 01; 233:8-15.
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GnRH Pulse Frequency Control of Fshb Gene Expression Is Mediated via ERK1/2 Regulation of ICER. Mol Endocrinol. 2016 Mar; 30(3):348-60.
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R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism. PLoS One. 2013; 8(7):e69616.
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Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells. Biol Reprod. 2007 Dec; 77(6):1073-80.
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Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1. Biol Reprod. 2006 Jun; 74(6):993-8.
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Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells. Endocrinology. 2005 Dec; 146(12):5503-13.
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GNRHR mutations in a woman with idiopathic hypogonadotropic hypogonadism highlight the differential sensitivity of luteinizing hormone and follicle-stimulating hormone to gonadotropin-releasing hormone. J Clin Endocrinol Metab. 2004 Jul; 89(7):3189-98.
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Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Mol Endocrinol. 2004 May; 18(5):1263-76.