Harvard Catalyst Profiles

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Loss of Heterozygosity

"Loss of Heterozygosity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.

This graph shows the total number of publications written about "Loss of Heterozygosity" by people in Harvard Catalyst Profiles by year, and whether "Loss of Heterozygosity" was a major or minor topic of these publication.
Bar chart showing 406 publications over 28 distinct years, with a maximum of 29 publications in 2001 and 2004
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.