Long-Term Synaptic Depression
"Long-Term Synaptic Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Concept/Terms
Long-Term Synaptic Depression- Long-Term Synaptic Depression
- Long Term Synaptic Depression
- Synaptic Depression, Long-Term
- Long-Term Depression, Physiological
- Depression, Physiological Long-Term
- Depressions, Physiological Long-Term
- Long Term Depression, Physiological
- Long-Term Depressions, Physiological
- Physiological Long-Term Depression
- Physiological Long-Term Depressions
- Long-Term Depression, Neurophysiological
- Depression, Neurophysiological Long-Term
- Depressions, Neurophysiological Long-Term
- Long Term Depression, Neurophysiological
- Long-Term Depressions, Neurophysiological
- Neurophysiological Long-Term Depression
- Neurophysiological Long-Term Depressions
- Long-Term Depression, Physiologic
- Long Term Depression, Physiologic
- Physiologic Long-Term Depression
- Long-Term Depression, Neurophysiologic
- Long Term Depression, Neurophysiologic
- Neurophysiologic Long-Term Depression
Depotentiation- Depotentiation
- Homosynaptic Depression
- Depression, Homosynaptic
Below are MeSH descriptors whose meaning is more general than "Long-Term Synaptic Depression".
Below are MeSH descriptors whose meaning is more specific than "Long-Term Synaptic Depression".
This graph shows the total number of publications written about "Long-Term Synaptic Depression" by people in Harvard Catalyst Profiles by year, and whether "Long-Term Synaptic Depression" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 3 | 4 |
| 2007 | 4 | 1 | 5 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
Below are the most recent publications written about "Long-Term Synaptic Depression" by people in Profiles.
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NMDARs in granule cells contribute to parallel fiber-Purkinje cell synaptic plasticity and motor learning. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
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Drug-Responsive Inhomogeneous Cortical Modulation by Direct Current Stimulation. Ann Neurol. 2020 09; 88(3):489-502.
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Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. Cell Rep. 2020 03 24; 30(12):4197-4208.e6.
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Soluble tau aggregates inhibit synaptic long-term depression and amyloid ß-facilitated LTD in vivo. Neurobiol Dis. 2019 07; 127:582-590.
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A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2. Cell Rep. 2019 01 29; 26(5):1089-1097.e3.
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Neurogenetic profiles delineate large-scale connectivity dynamics of the human brain. Nat Commun. 2018 09 24; 9(1):3876.
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Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory. Neuron. 2017 Aug 30; 95(5):1089-1102.e5.
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Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation. J Neurosci. 2017 02 15; 37(7):1747-1756.
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Direct current stimulation induces mGluR5-dependent neocortical plasticity. Ann Neurol. 2016 08; 80(2):233-46.
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The 5-hydroxytryptamine4 receptor enables differentiation of informational content and encoding in the hippocampus. Hippocampus. 2016 07; 26(7):875-91.