Harvard Catalyst Profiles

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Locus Control Region

"Locus Control Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate GENETIC TRANSCRIPTION by opening and remodeling CHROMATIN structure. It may also have enhancer activity.


This graph shows the total number of publications written about "Locus Control Region" by people in Harvard Catalyst Profiles by year, and whether "Locus Control Region" was a major or minor topic of these publication.
Bar chart showing 19 publications over 11 distinct years, with a maximum of 4 publications in 1998
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.