"Lipoproteins, VLDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of very light (0.93-1.006 g/ml) large size (30-80 nm) particles with a core composed mainly of TRIGLYCERIDES and a surface monolayer of PHOSPHOLIPIDS and CHOLESTEROL into which are imbedded the apolipoproteins B, E, and C. VLDL facilitates the transport of endogenously made triglycerides to extrahepatic tissues. As triglycerides and Apo C are removed, VLDL is converted to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LOW-DENSITY LIPOPROTEINS from which cholesterol is delivered to the extrahepatic tissues.
MeSH Number(s)
D10.532.599
D12.776.521.622
Concept/Terms
Lipoproteins, VLDL- Lipoproteins, VLDL
- VLDL Lipoproteins
- Prebeta-Lipoproteins
- Prebeta Lipoproteins
- Very-Low-Density Lipoproteins
- Lipoproteins, Very-Low-Density
- Very Low Density Lipoproteins
- Pre-beta-Lipoproteins
- Pre beta Lipoproteins
Below are MeSH descriptors whose meaning is more general than "Lipoproteins, VLDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, VLDL".
This graph shows the total number of publications written about "Lipoproteins, VLDL" by people in Harvard Catalyst Profiles by year, and whether "Lipoproteins, VLDL" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 3 | 5 |
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 2 | 5 | 7 |
| 1997 | 2 | 3 | 5 |
| 1998 | 1 | 5 | 6 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 3 | 4 |
| 2002 | 3 | 2 | 5 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 5 | 7 |
| 2007 | 4 | 1 | 5 |
| 2008 | 5 | 1 | 6 |
| 2009 | 2 | 0 | 2 |
| 2010 | 3 | 6 | 9 |
| 2011 | 5 | 7 | 12 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 4 | 6 |
| 2014 | 2 | 2 | 4 |
| 2015 | 4 | 5 | 9 |
| 2016 | 5 | 3 | 8 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 2 | 4 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 1 | 3 |
Below are the most recent publications written about "Lipoproteins, VLDL" by people in Profiles.
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Effects of PNPLA3 I148M on hepatic lipid and very-low-density lipoprotein metabolism in humans. J Intern Med. 2022 02; 291(2):218-223.
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Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4. J Lipid Res. 2021; 62:100091.
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Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease. Clin Chem. 2021 01 08; 67(1):183-196.
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Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans. JCI Insight. 2020 12 17; 5(24).
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An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes. Biochemistry. 2020 11 17; 59(45):4321-4335.
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Association of the Mediterranean Diet With Onset of Diabetes in the Women's Health Study. JAMA Netw Open. 2020 11 02; 3(11):e2025466.
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Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells. J Lipid Res. 2020 02; 61(2):205-218.
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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis. Cell. 2019 11 27; 179(6):1276-1288.e14.
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A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Nat Commun. 2019 10 21; 10(1):4788.
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Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis. Hepatology. 2019 08; 70(2):496-510.