"Lamin Type A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.
Below are MeSH descriptors whose meaning is more general than "Lamin Type A".
Below are MeSH descriptors whose meaning is more specific than "Lamin Type A".
This graph shows the total number of publications written about "Lamin Type A" by people in Harvard Catalyst Profiles by year, and whether "Lamin Type A" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 4 | 2 | 6 |
| 2005 | 3 | 2 | 5 |
| 2006 | 3 | 4 | 7 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 3 | 4 |
| 2012 | 2 | 4 | 6 |
| 2013 | 2 | 2 | 4 |
| 2014 | 3 | 5 | 8 |
| 2015 | 3 | 5 | 8 |
| 2016 | 4 | 3 | 7 |
| 2017 | 4 | 1 | 5 |
| 2018 | 1 | 6 | 7 |
| 2019 | 0 | 2 | 2 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 11 | 11 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Lamin Type A" by people in Profiles.
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Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome. Elife. 2023 03 17; 12.
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Intrinsic Atrial Myopathy Precedes Left Ventricular Dysfunction and Predicts Atrial Fibrillation in Lamin A/C Cardiomyopathy. Circ Genom Precis Med. 2023 02; 16(1):e003480.
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Efficacy and Safety of ARRY-371797 in LMNA-Related Dilated Cardiomyopathy: A Phase 2 Study. Circ Genom Precis Med. 2023 02; 16(1):e003730.
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Timing of cardioverter-defibrillator implantation in patients with cardiac laminopathies-External validation of the LMNA-risk ventricular tachyarrhythmia calculator. Heart Rhythm. 2023 03; 20(3):423-429.
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Long-Term Efficacy and Safety of ARRY-371797 (PF-07265803) in Patients With Lamin A/C-Related Dilated Cardiomyopathy. Am J Cardiol. 2022 11 15; 183:93-98.
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LMNA Variants and Risk of Adult-Onset Cardiac Disease. J Am Coll Cardiol. 2022 07 05; 80(1):50-59.
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Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. Geroscience. 2023 04; 45(2):1231-1236.
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Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics. Proc Natl Acad Sci U S A. 2022 04 26; 119(17):e2121816119.
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Pregnancy and Progression of Cardiomyopathy in Women With LMNA Genotype-Positive. J Am Heart Assoc. 2022 04 19; 11(8):e024960.
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The nuclear lamina binds the EBV genome during latency and regulates viral gene expression. PLoS Pathog. 2022 04; 18(4):e1010400.