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Kininogen, High-Molecular-Weight

"Kininogen, High-Molecular-Weight" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)


This graph shows the total number of publications written about "Kininogen, High-Molecular-Weight" by people in Harvard Catalyst Profiles by year, and whether "Kininogen, High-Molecular-Weight" was a major or minor topic of these publication.
Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 2011
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.