Keratin-17

"Keratin-17" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type I keratin found associated with KERATIN-6 in rapidly proliferating squamous epithelial tissue. Mutations in the gene for keratin-17 have been associated with PACHYONYCHIA CONGENITA, TYPE 2.

Descriptor ID

D053537

MeSH Number(s)

D05.750.078.593.450.300.700

D12.776.220.475.450.300.700

D12.776.860.607.300.700

Concept/Terms

Keratin-17

Below are MeSH descriptors whose meaning is more general than "Keratin-17".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Polymers [D05.750]
Biopolymers [D05.750.078]
Intermediate Filament Proteins [D05.750.078.593]
Keratins [D05.750.078.593.450]
Keratins, Type I [D05.750.078.593.450.300]
Keratin-17 [D05.750.078.593.450.300.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Cytoskeletal Proteins [D12.776.220]
Intermediate Filament Proteins [D12.776.220.475]
Keratins [D12.776.220.475.450]
Keratins, Type I [D12.776.220.475.450.300]
Keratin-17 [D12.776.220.475.450.300.700]
Scleroproteins [D12.776.860]
Keratins [D12.776.860.607]
Keratins, Type I [D12.776.860.607.300]
Keratin-17 [D12.776.860.607.300.700]

Below are MeSH descriptors whose meaning is related to "Keratin-17".

Below are MeSH descriptors whose meaning is more specific than "Keratin-17".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Keratin-17" by people in Harvard Catalyst Profiles by year, and whether "Keratin-17" was a major or minor topic of these publication.

Bar chart showing 16 publications over 9 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	0	1	1
2009	0	1	1
2011	1	0	1
2013	1	3	4
2014	1	1	2
2016	2	1	3
2018	2	0	2
2020	0	1	1
2022	0	1	1

Below are the most recent publications written about "Keratin-17" by people in Profiles.

Use of Cytokeratin 17 in the Differentiation Between Desmoplastic Trichilemmoma and Cutaneous Basal Cell Carcinoma. Am J Dermatopathol. 2022 Dec 01; 44(12):886-890.

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Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation. Cell Death Dis. 2020 01 10; 11(1):21.

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Identification of a novel substitution mutation (R103C) in the rod domain of the keratin 17 gene associated with pachyonychia congenita type 2. Int J Dermatol. 2019 Feb; 58(2):233-236.

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Elevated expression of keratin 17 in oropharyngeal squamous cell carcinoma is associated with decreased survival. Head Neck. 2018 08; 40(8):1788-1798.

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Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer. Hum Pathol. 2017 04; 62:23-32.

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Cytokeratin 17 is highly sensitive in discriminating cutaneous lymphadenoma (a distinct trichoblastoma variant) from basal cell carcinoma. J Cutan Pathol. 2016 May; 43(5):422-9.

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Choristomatous Respiratory Cyst Restricted to the Upper Eyelid. Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb; 32(1):e15-8.

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Ruptured canthal steatocystoma simplex presenting as a lacrimal sac mass. Clin Exp Ophthalmol. 2015 May-Jun; 43(4):385-7.

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Cytokeratin 17: an adjunctive marker of invasion in squamous neoplastic lesions of the anus. Am J Surg Pathol. 2014 Jan; 38(1):78-85.

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Ectopic (choristomatous) orbital respiratory cyst: histopathology and immunohistochemistry. Surv Ophthalmol. 2014 May-Jun; 59(3):328-33.

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Int J Dermatol
Oral Oncol
J Cutan Pathol
Hum Pathol
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Arch Pathol Lab Med
Am J Surg Pathol
Am J Dermatopathol
Cell Death Dis
Am J Ophthalmol