"KB Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This line KB is now known to be a subline of the ubiquitous KERATIN-forming tumor cell line HeLa. It was originally thought to be derived from an epidermal carcinoma of the mouth, but was subsequently found, based on isoenzyme analysis, HeLa marker chromosomes, and DNA fingerprinting, to have been established via contamination by HELA CELLS. The cells are positive for keratin by immunoperoxidase staining. KB cells have been reported to contain human papillomavirus18 (HPV-18) sequences.
MeSH Number(s)
A11.251.210.190.400.500
A11.251.860.180.400.500
A11.436.340.500
Concept/Terms
KB Cells- KB Cells
- Cell, KB
- Cells, KB
- KB Cell
- HeLa-KB Cells
- Cell, HeLa-KB
- Cells, HeLa-KB
- HeLa KB Cells
- HeLa-KB Cell
Below are MeSH descriptors whose meaning is more general than "KB Cells".
Below are MeSH descriptors whose meaning is more specific than "KB Cells".
This graph shows the total number of publications written about "KB Cells" by people in Harvard Catalyst Profiles by year, and whether "KB Cells" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
Below are the most recent publications written about "KB Cells" by people in Profiles.
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Epigallocatechin-3-gallate sensitises multidrug-resistant oral carcinoma xenografts to vincristine sulfate. FEBS Open Bio. 2020 07; 10(7):1403-1413.
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4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin. Eur J Med Chem. 2016 Oct 21; 122:520-529.
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Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand. Biomaterials. 2016 Jan; 77:98-110.
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Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy. Chem Commun (Camb). 2015 Apr 04; 51(26):5687-90.
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3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation. Eur J Med Chem. 2015 Jan 27; 90:184-94.
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Stimuli-responsive photoacoustic nanoswitch for in vivo sensing applications. ACS Nano. 2014 Aug 26; 8(8):8363-73.
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Aggregate enhanced trimodal porphyrin shell microbubbles for ultrasound, photoacoustic, and fluorescence imaging. Bioconjug Chem. 2014 Apr 16; 25(4):796-801.
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Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway. Oncol Rep. 2014 Feb; 31(2):755-62.
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DNA self-assembly of targeted near-infrared-responsive gold nanoparticles for cancer thermo-chemotherapy. Angew Chem Int Ed Engl. 2012 Nov 19; 51(47):11853-7.
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Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic. Mol Pharm. 2012 Sep 04; 9(9):2669-2676.