Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Janus Kinases

"Janus Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.

This graph shows the total number of publications written about "Janus Kinases" by people in Harvard Catalyst Profiles by year, and whether "Janus Kinases" was a major or minor topic of these publication.
Bar chart showing 118 publications over 25 distinct years, with a maximum of 13 publications in 2014
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.