Isoleucine

"Isoleucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.

Descriptor ID

D007532

MeSH Number(s)

D12.125.070.577

D12.125.142.383

Concept/Terms

Isoleucine

Alloisoleucine

Below are MeSH descriptors whose meaning is more general than "Isoleucine".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Branched-Chain [D12.125.070]
Isoleucine [D12.125.070.577]
Amino Acids, Essential [D12.125.142]
Isoleucine [D12.125.142.383]

Below are MeSH descriptors whose meaning is related to "Isoleucine".

Below are MeSH descriptors whose meaning is more specific than "Isoleucine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Isoleucine" by people in Harvard Catalyst Profiles by year, and whether "Isoleucine" was a major or minor topic of these publication.

Bar chart showing 64 publications over 30 distinct years, with a maximum of 5 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	3	4
1995	0	1	1
1996	0	1	1
1997	0	2	2
1998	1	4	5
1999	1	2	3
2000	2	1	3
2001	1	3	4
2002	0	3	3
2003	1	0	1
2005	0	1	1
2006	0	3	3
2007	0	2	2
2008	0	3	3
2009	0	1	1
2010	0	1	1
2011	2	0	2
2012	0	1	1
2013	0	2	2
2014	0	3	3
2015	1	2	3
2016	0	1	1
2017	0	1	1
2018	1	3	4
2019	1	0	1
2020	0	1	1
2021	0	3	3
2022	0	2	2
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "Isoleucine" by people in Profiles.

Resilience and proteome response of Escherichia coli to high levels of isoleucine mistranslation. Int J Biol Macromol. 2024 Mar; 262(Pt 1):130068.

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Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures, and Bone Mineral Density of the Hip and Spine. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1358-e1364.

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The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study. BMC Med. 2022 10 28; 20(1):414.

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Immunometabolism - The Role of Branched-Chain Amino Acids. Front Immunol. 2022; 13:886822.

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Transthyretin V142I Genetic Variant and Cardiac Remodeling, Injury, and Heart Failure Risk in Black Adults. JACC Heart Fail. 2022 02; 10(2):129-138.

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Branched-Chain Amino Acids and Risk of Breast Cancer. JNCI Cancer Spectr. 2021 10; 5(5).

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Integrated metabolomic analysis and cytokine profiling define clusters of immuno-metabolic correlation in new-onset psoriasis. Sci Rep. 2021 05 18; 11(1):10472.

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Increased branched-chain amino acids at baseline and hours before a spontaneous seizure in the human epileptic brain. Epilepsia. 2021 06; 62(6):e88-e97.

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Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer. Cancer Cell. 2020 02 10; 37(2):147-156.

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Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris. J Biomol NMR. 2019 Dec; 73(12):687-697.

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