Harvard Catalyst Profiles

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Inverted Repeat Sequences

"Inverted Repeat Sequences" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Copies of nucleic acid sequence that are arranged in opposing orientation. They may lie adjacent to each other (tandem) or be separated by some sequence that is not part of the repeat (hyphenated). They may be true palindromic repeats, i.e. read the same backwards as forward, or complementary which reads as the base complement in the opposite orientation. Complementary inverted repeats have the potential to form hairpin loop or stem-loop structures which results in cruciform structures (such as CRUCIFORM DNA) when the complementary inverted repeats occur in double stranded regions.


This graph shows the total number of publications written about "Inverted Repeat Sequences" by people in Harvard Catalyst Profiles by year, and whether "Inverted Repeat Sequences" was a major or minor topic of these publication.
Bar chart showing 40 publications over 12 distinct years, with a maximum of 14 publications in 2013
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.