Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Integrin alphaVbeta3

"Integrin alphaVbeta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).


publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "Integrin alphaVbeta3" by people in Harvard Catalyst Profiles by year, and whether "Integrin alphaVbeta3" was a major or minor topic of these publication.
To see the data from this visualization as text,
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.