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Integrin alpha2beta1

"Integrin alpha2beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.


This graph shows the total number of publications written about "Integrin alpha2beta1" by people in Harvard Catalyst Profiles by year, and whether "Integrin alpha2beta1" was a major or minor topic of these publication.
Bar chart showing 16 publications over 11 distinct years, with a maximum of 3 publications in 2009
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.