"Integrases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.
Below are MeSH descriptors whose meaning is more general than "Integrases".
Below are MeSH descriptors whose meaning is more specific than "Integrases".
This graph shows the total number of publications written about "Integrases" by people in Harvard Catalyst Profiles by year, and whether "Integrases" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 6 | 6 |
1995 | 1 | 4 | 5 |
1996 | 4 | 1 | 5 |
1997 | 5 | 1 | 6 |
1998 | 3 | 1 | 4 |
1999 | 5 | 3 | 8 |
2000 | 6 | 2 | 8 |
2001 | 4 | 6 | 10 |
2002 | 1 | 1 | 2 |
2003 | 1 | 9 | 10 |
2004 | 1 | 9 | 10 |
2005 | 3 | 11 | 14 |
2006 | 3 | 11 | 14 |
2007 | 2 | 16 | 18 |
2008 | 3 | 21 | 24 |
2009 | 2 | 15 | 17 |
2010 | 4 | 11 | 15 |
2011 | 12 | 13 | 25 |
2012 | 3 | 10 | 13 |
2013 | 7 | 12 | 19 |
2014 | 6 | 17 | 23 |
2015 | 8 | 9 | 17 |
2016 | 3 | 10 | 13 |
2017 | 3 | 10 | 13 |
2018 | 1 | 6 | 7 |
2019 | 1 | 6 | 7 |
2020 | 3 | 5 | 8 |
2021 | 6 | 3 | 9 |
2022 | 6 | 3 | 9 |
2023 | 2 | 6 | 8 |
Below are the most recent publications written about "Integrases" by people in Profiles.
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Impact of Integrase Strand Transfer Inhibitors on Cognition in the HAILO Cohort. J Acquir Immune Defic Syndr. 2023 12 15; 94(5):437-444.
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Integrase strand-transfer inhibitor use and cardiovascular events in adults with HIV: an emulation of target trials in the HIV-CAUSAL Collaboration and the Antiretroviral Therapy Cohort Collaboration. Lancet HIV. 2023 Nov; 10(11):e723-e732.
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Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish. Dev Cell. 2023 Nov 20; 58(22):2614-2626.e7.
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Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort. J Antimicrob Chemother. 2023 08 02; 78(8):2000-2007.
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Extracellular communication between brain cells through functional transfer of Cre mRNA mediated by extracellular vesicles. Mol Ther. 2023 07 05; 31(7):2220-2239.
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Evidence for RNA or protein transport from somatic tissues to the male reproductive tract in mouse. Elife. 2023 03 27; 12.
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Emerging integrase strand transfer inhibitor drug resistance mutations among children and adults on ART in Tanzania: findings from a national representative HIV drug resistance survey. J Antimicrob Chemother. 2023 03 02; 78(3):779-787.
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Predicted effects of the introduction of long-acting injectable cabotegravir pre-exposure prophylaxis in sub-Saharan Africa: a modelling study. Lancet HIV. 2023 04; 10(4):e254-e265.
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Myh6 promoter-driven Cre recombinase excises floxed DNA fragments in a subset of male germline cells. J Mol Cell Cardiol. 2023 02; 175:62-66.
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Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases. Nat Biotechnol. 2023 04; 41(4):500-512.