"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
MeSH Number(s)
D06.472.699.587.200.500.625
D12.644.548.586.200.500.625
Concept/Terms
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in Harvard Catalyst Profiles by year, and whether "Insulin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 26 | 32 | 58 |
| 1992 | 28 | 33 | 61 |
| 1993 | 38 | 36 | 74 |
| 1994 | 31 | 35 | 66 |
| 1995 | 29 | 34 | 63 |
| 1996 | 40 | 23 | 63 |
| 1997 | 39 | 40 | 79 |
| 1998 | 25 | 43 | 68 |
| 1999 | 52 | 40 | 92 |
| 2000 | 39 | 61 | 100 |
| 2001 | 48 | 55 | 103 |
| 2002 | 55 | 65 | 120 |
| 2003 | 48 | 74 | 122 |
| 2004 | 50 | 79 | 129 |
| 2005 | 50 | 62 | 112 |
| 2006 | 55 | 77 | 132 |
| 2007 | 52 | 92 | 144 |
| 2008 | 60 | 101 | 161 |
| 2009 | 58 | 94 | 152 |
| 2010 | 73 | 77 | 150 |
| 2011 | 59 | 90 | 149 |
| 2012 | 84 | 90 | 174 |
| 2013 | 68 | 84 | 152 |
| 2014 | 69 | 97 | 166 |
| 2015 | 66 | 85 | 151 |
| 2016 | 73 | 80 | 153 |
| 2017 | 59 | 78 | 137 |
| 2018 | 48 | 61 | 109 |
| 2019 | 61 | 82 | 143 |
| 2020 | 30 | 49 | 79 |
| 2021 | 11 | 12 | 23 |
Below are the most recent publications written about "Insulin" by people in Profiles.
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GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. Nat Commun. 2021 07 07; 12(1):4178.
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TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data. Nucleic Acids Res. 2021 07 02; 49(W1):W641-W653.
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Assessing real-world medication data completeness. J Biomed Inform. 2021 07; 119:103847.
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A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes. Sci Transl Med. 2021 06 02; 13(596).
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Insulin Resistance Is Not Sustained Following Denervation in Glycolytic Skeletal Muscle. Int J Mol Sci. 2021 May 06; 22(9).
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17a-Estradiol Modulates IGF1 and Hepatic Gene Expression in a Sex-Specific Manner. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):778-785.
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Correlates of analog vs human basal insulin use among individuals with type 2 diabetes: A cross-sectional study. Diabetes Res Clin Pract. 2021 May; 175:108825.
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Insulin-Dependent Status Influences Post-Procedural Outcomes in Diabetic Patients Following Lower Extremity Endovascular Intervention for Peripheral Arterial Disease. Cardiovasc Intervent Radiol. 2021 Aug; 44(8):1165-1173.
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Data-driven curation process for describing the blood glucose management in the intensive care unit. Sci Data. 2021 03 10; 8(1):80.
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Preoperative Management of Endocrine, Hormonal, and Urologic Medications: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clin Proc. 2021 06; 96(6):1655-1669.