Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Immunoglobulin Joining Region

"Immunoglobulin Joining Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.


This graph shows the total number of publications written about "Immunoglobulin Joining Region" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin Joining Region" was a major or minor topic of these publication.
Bar chart showing 31 publications over 15 distinct years, with a maximum of 5 publications in 1993
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.