Harvard Catalyst Profiles

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Immunoglobulin Idiotypes

"Immunoglobulin Idiotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.


This graph shows the total number of publications written about "Immunoglobulin Idiotypes" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin Idiotypes" was a major or minor topic of these publication.
Bar chart showing 65 publications over 18 distinct years, with a maximum of 14 publications in 1991
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.