Harvard Catalyst Profiles

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Immunoglobulin Fc Fragments

"Immunoglobulin Fc Fragments" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.


This graph shows the total number of publications written about "Immunoglobulin Fc Fragments" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin Fc Fragments" was a major or minor topic of these publication.
Bar chart showing 125 publications over 27 distinct years, with a maximum of 13 publications in 2014 and 2016
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.