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Immunoglobulin Fab Fragments

"Immunoglobulin Fab Fragments" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.


This graph shows the total number of publications written about "Immunoglobulin Fab Fragments" by people in Harvard Catalyst Profiles by year, and whether "Immunoglobulin Fab Fragments" was a major or minor topic of these publication.
Bar chart showing 298 publications over 30 distinct years, with a maximum of 21 publications in 2001 and 2002
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.