Hyperlipidemia, Familial Combined
"Hyperlipidemia, Familial Combined" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of familial lipid metabolism disorder characterized by a variable pattern of elevated plasma CHOLESTEROL and/or TRIGLYCERIDES. Multiple genes on different chromosomes may be involved, such as the major late transcription factor (UPSTREAM STIMULATORY FACTORS) on CHROMOSOME 1.
MeSH Number(s)
C16.320.565.398.450
C18.452.584.500.500.438
C18.452.648.398.450
Concept/Terms
Hyperlipidemia, Familial Combined- Hyperlipidemia, Familial Combined
- Combined Hyperlipidemia, Familial
- Combined Hyperlipidemias, Familial
- Familial Combined Hyperlipidemia
- Familial Combined Hyperlipidemias
- Hyperlipidemias, Familial Combined
- Hyperlipidemia, Multiple Lipoprotein-Type
- Hyperlipidemia, Multiple Lipoprotein Type
- Hyperlipidemias, Multiple Lipoprotein-Type
- Lipoprotein-Type Hyperlipidemia, Multiple
- Lipoprotein-Type Hyperlipidemias, Multiple
- Multiple Lipoprotein-Type Hyperlipidemia
- Multiple Lipoprotein-Type Hyperlipidemias
Below are MeSH descriptors whose meaning is more general than "Hyperlipidemia, Familial Combined".
- Diseases [C]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Metabolism, Inborn Errors [C16.320.565]
- Lipid Metabolism, Inborn Errors [C16.320.565.398]
- Hyperlipidemia, Familial Combined [C16.320.565.398.450]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Lipid Metabolism Disorders [C18.452.584]
- Dyslipidemias [C18.452.584.500]
- Hyperlipidemias [C18.452.584.500.500]
- Hyperlipidemia, Familial Combined [C18.452.584.500.500.438]
- Metabolism, Inborn Errors [C18.452.648]
- Lipid Metabolism, Inborn Errors [C18.452.648.398]
- Hyperlipidemia, Familial Combined [C18.452.648.398.450]
Below are MeSH descriptors whose meaning is more specific than "Hyperlipidemia, Familial Combined".
This graph shows the total number of publications written about "Hyperlipidemia, Familial Combined" by people in Harvard Catalyst Profiles by year, and whether "Hyperlipidemia, Familial Combined" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2016 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Hyperlipidemia, Familial Combined" by people in Profiles.
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The clinical utility of polygenic risk scores for combined hyperlipidemia. Curr Opin Lipidol. 2023 Apr 01; 34(2):44-51.
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Familial combined hyperlipidemia and hyperlipoprotein(a) as phenotypic mimics of familial hypercholesterolemia: Frequencies, associations and predictions. J Clin Lipidol. 2016 Nov - Dec; 10(6):1329-1337.e3.
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The Contribution of GWAS Loci in Familial Dyslipidemias. PLoS Genet. 2016 05; 12(5):e1006078.
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Progress in the care of common inherited atherogenic disorders of apolipoprotein B metabolism. Nat Rev Endocrinol. 2016 08; 12(8):467-84.
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Utility of contrast-enhanced ultrasonography for qualitative imaging of atherosclerosis in Watanabe heritable hyperlipidemic rabbits: initial experimental study. Jpn J Radiol. 2010 Nov; 28(9):656-62.
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Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study. Int J Clin Pharmacol Ther. 2004 Dec; 42(12):672-9.
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Increased circulating malondialdehyde-modified LDL in the patients with familial combined hyperlipidemia and its relation with the hepatic lipase activity. Atherosclerosis. 2004 Jan; 172(1):181-7.
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Fine mapping of Hyplip1 and the human homolog, a potential locus for FCHL. Mamm Genome. 2001 Mar; 12(3):238-45.
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Replication of linkage of familial combined hyperlipidemia to chromosome 1q with additional heterogeneous effect of apolipoprotein A-I/C-III/A-IV locus. The NHLBI Family Heart Study. Arterioscler Thromb Vasc Biol. 2000 Oct; 20(10):2275-80.
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Familial combined hyperlipidaemia: use of stable isotopes to demonstrate overproduction of very low-density lipoprotein apolipoprotein B by the liver. J Inherit Metab Dis. 1991; 14(6):915-22.