"Hybridomas" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
MeSH Number(s)
A11.251.353.485
A11.251.600.485
Below are MeSH descriptors whose meaning is more general than "Hybridomas".
Below are MeSH descriptors whose meaning is more specific than "Hybridomas".
This graph shows the total number of publications written about "Hybridomas" by people in Harvard Catalyst Profiles by year, and whether "Hybridomas" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 11 | 13 |
| 1994 | 2 | 8 | 10 |
| 1995 | 2 | 7 | 9 |
| 1996 | 1 | 5 | 6 |
| 1997 | 1 | 4 | 5 |
| 1998 | 0 | 9 | 9 |
| 1999 | 0 | 4 | 4 |
| 2000 | 1 | 8 | 9 |
| 2001 | 1 | 7 | 8 |
| 2002 | 2 | 10 | 12 |
| 2003 | 1 | 8 | 9 |
| 2004 | 0 | 10 | 10 |
| 2005 | 0 | 7 | 7 |
| 2006 | 1 | 6 | 7 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 0 | 5 | 5 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 2 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 2 | 0 | 2 |
| 2019 | 6 | 3 | 9 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 9 | 11 |
| 2022 | 0 | 14 | 14 |
Below are the most recent publications written about "Hybridomas" by people in Profiles.
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Determining the Class and Subclass of Monoclonal Antibodies Using Antibody Capture on Anti-Immunoglobulin Antibody-Coated Plates. Cold Spring Harb Protoc. 2022 08 01; 2022(8):pdb.prot103234.
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Generating Monoclonal Antibodies. Cold Spring Harb Protoc. 2022 08 01; 2022(8):Pdb.top103036.
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Immunizing Animals. Cold Spring Harb Protoc. 2022 07 12; 2022(7):Pdb.top100180.
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Hybridoma Screening by Antibody Capture: Flow Cytometry/FACS with Whole Cells to Detect Cell-Surface Binding. Cold Spring Harb Protoc. 2022 06 24; 2022(6):Pdb.prot103077.
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Hybridoma Screening by Antibody Capture: Flow Cytometry/FACS with Permeabilized Cells to Detect Intracellular Binding. Cold Spring Harb Protoc. 2022 06 24; 2022(6):Pdb.prot103085.
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Hybridoma Screening by Antibody Capture: Enzyme-Linked Detection (Indirect ELISA) in Polyvinyl Chloride Wells. Cold Spring Harb Protoc. 2022 06 07; 2022(5):Pdb.prot103044.
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Hybridoma Screening by Antibody Capture: Immunohistochemistry. Cold Spring Harb Protoc. 2022 06 07; 2022(5):Pdb.prot103119.
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Determining the Class and Subclass of a Monoclonal Antibody by Ouchterlony Double-Diffusion Assays. Cold Spring Harb Protoc. 2022 06 07; 2022(5):Pdb.prot103218.
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Development of functional antibodies against influenza B virus by activation-induced cytidine deaminase in hybridoma cells. Virol Sin. 2022 08; 37(4):619-622.
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Hybridoma Screening by Antibody Capture: Detection of Intracellular Binding by Immunofluorescence. Cold Spring Harb Protoc. 2022 02 01; 2022(2).