Harvard Catalyst Profiles

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Histone Deacetylases

"Histone Deacetylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.


This graph shows the total number of publications written about "Histone Deacetylases" by people in Harvard Catalyst Profiles by year, and whether "Histone Deacetylases" was a major or minor topic of these publication.
Bar chart showing 421 publications over 23 distinct years, with a maximum of 40 publications in 2009
To see the data from this visualization as text, click here.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.