Harvard Catalyst Profiles

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Histone Deacetylases

"Histone Deacetylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.


This graph shows the total number of publications written about "Histone Deacetylases" by people in Harvard Catalyst Profiles by year, and whether "Histone Deacetylases" was a major or minor topic of these publication.
Bar chart showing 437 publications over 25 distinct years, with a maximum of 37 publications in 2009
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.