Hemin

"Hemin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Chloro(7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N(21),N(22),N(23),N(24)) ferrate(2-) dihydrogen.

Descriptor ID

D006427

MeSH Number(s)

D03.383.129.578.840.500.640.587.462

D03.549.909.500.640.587.462

D04.345.783.500.640.587.462

D23.767.727.640.587.462

Concept/Terms

Hemin

Ferrihaem

Panhematin

Ferriprotoporphyrin IX

Hematin

Alkaline Hematin D-575

Ferriprotoporphyrin

Below are MeSH descriptors whose meaning is more general than "Hemin".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Pyrroles [D03.383.129.578]
Tetrapyrroles [D03.383.129.578.840]
Porphyrins [D03.383.129.578.840.500]
Metalloporphyrins [D03.383.129.578.840.500.640]
Heme [D03.383.129.578.840.500.640.587]
Hemin [D03.383.129.578.840.500.640.587.462]
Heterocyclic Compounds with 4 or More Rings [D03.549]
Tetrapyrroles [D03.549.909]
Porphyrins [D03.549.909.500]
Metalloporphyrins [D03.549.909.500.640]
Heme [D03.549.909.500.640.587]
Hemin [D03.549.909.500.640.587.462]
Polycyclic Compounds [D04]
Macrocyclic Compounds [D04.345]
Tetrapyrroles [D04.345.783]
Porphyrins [D04.345.783.500]
Metalloporphyrins [D04.345.783.500.640]
Heme [D04.345.783.500.640.587]
Hemin [D04.345.783.500.640.587.462]
Biological Factors [D23]
Pigments, Biological [D23.767]
Porphyrins [D23.767.727]
Metalloporphyrins [D23.767.727.640]
Heme [D23.767.727.640.587]
Hemin [D23.767.727.640.587.462]

Below are MeSH descriptors whose meaning is related to "Hemin".

Below are MeSH descriptors whose meaning is more specific than "Hemin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hemin" by people in Harvard Catalyst Profiles by year, and whether "Hemin" was a major or minor topic of these publication.

Bar chart showing 33 publications over 17 distinct years, with a maximum of 4 publications in 1996 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	1	4
1997	1	1	2
1998	0	1	1
2000	0	2	2
2001	0	1	1
2002	1	1	2
2003	1	0	1
2004	0	1	1
2005	0	1	1
2006	1	2	3
2011	1	1	2
2012	1	0	1
2013	2	0	2
2014	2	2	4
2015	1	0	1
2018	0	3	3
2019	1	1	2

Below are the most recent publications written about "Hemin" by people in Profiles.

Intracellular Fe2+ accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage. Sci Rep. 2019 04 17; 9(1):6228.

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Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. Nature. 2019 04; 568(7751):254-258.

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A novel Nrf2 activator, RS9, attenuates secondary brain injury after intracerebral hemorrhage in sub-acute phase. Brain Res. 2018 12 15; 1701:137-145.

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Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells. Cell Metab. 2018 10 02; 28(4):573-587.e13.

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Hemopexin increases the neurotoxicity of hemoglobin when haptoglobin is absent. J Neurochem. 2018 06; 145(6):464-473.

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Energetics underlying hemin extraction from human hemoglobin by Staphylococcus aureus. J Biol Chem. 2018 05 04; 293(18):6942-6957.

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Control of hmu Heme Uptake Genes in Yersinia pseudotuberculosis in Response to Iron Sources. Front Cell Infect Microbiol. 2018; 8:47.

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Early Onset of Kinetic Roughening due to a Finite Step Width in Hematin Crystallization. Phys Rev Lett. 2017 Nov 10; 119(19):198101.

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Deconstructing Quinoline-Class Antimalarials to Identify Fundamental Physicochemical Properties of Beta-Hematin Crystal Growth Inhibitors. Chemistry. 2017 Oct 04; 23(55):13638-13647.

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Antimalarials inhibit hematin crystallization by unique drug-surface site interactions. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7531-7536.

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