"Hemidesmosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS.
Below are MeSH descriptors whose meaning is more general than "Hemidesmosomes".
Below are MeSH descriptors whose meaning is more specific than "Hemidesmosomes".
This graph shows the total number of publications written about "Hemidesmosomes" by people in Harvard Catalyst Profiles by year, and whether "Hemidesmosomes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
Below are the most recent publications written about "Hemidesmosomes" by people in Profiles.
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Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function. PLoS One. 2012; 7(9):e43857.
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The calcium/calcineurin pathway promotes hemidesmosome stability through inhibition of ß4 integrin phosphorylation. J Biol Chem. 2012 Sep 21; 287(39):32440-9.
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aVß6 integrin promotes corneal wound healing. Invest Ophthalmol Vis Sci. 2011 Oct 31; 52(11):8505-13.
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Interaction of nectin-like molecule 2 with integrin alpha6beta4 and inhibition of disassembly of integrin alpha6beta4 from hemidesmosomes. J Biol Chem. 2011 Oct 21; 286(42):36667-76.
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Role of ß4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. Lab Invest. 2011 Oct; 91(10):1414-26.
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The impact of de-epithelialization of the amniotic membrane matrix on morphology of cultured human limbal epithelial cells subject to eye bank storage. Cornea. 2010 Apr; 29(4):439-45.
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Phosphorylation of a novel site on the {beta}4 integrin at the trailing edge of migrating cells promotes hemidesmosome disassembly. Mol Biol Cell. 2009 Jan; 20(1):56-67.
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Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells. Dev Biol. 2007 Dec 15; 312(2):484-500.
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Lung development in laminin gamma2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation. Respir Res. 2006 Feb 16; 7:28.
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Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid. Blood. 2006 Feb 01; 107(3):1063-9.