Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Helix-Turn-Helix Motifs

"Helix-Turn-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)


This graph shows the total number of publications written about "Helix-Turn-Helix Motifs" by people in Harvard Catalyst Profiles by year, and whether "Helix-Turn-Helix Motifs" was a major or minor topic of these publication.
Bar chart showing 12 publications over 10 distinct years, with a maximum of 2 publications in 2002 and 2003
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.