"Glucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)
MeSH Number(s)
D06.472.699.587.469.500
D12.644.548.586.469.500
Concept/Terms
Glucagon- Glucagon
- Proglucagon (33-61)
- HG-Factor
- HG Factor
- Hyperglycemic-Glycogenolytic Factor
- Hyperglycemic Glycogenolytic Factor
- Glucagon (1-29)
- Glukagon
Below are MeSH descriptors whose meaning is more general than "Glucagon".
Below are MeSH descriptors whose meaning is more specific than "Glucagon".
This graph shows the total number of publications written about "Glucagon" by people in Harvard Catalyst Profiles by year, and whether "Glucagon" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 3 | 6 |
| 1994 | 1 | 3 | 4 |
| 1995 | 6 | 4 | 10 |
| 1996 | 2 | 3 | 5 |
| 1997 | 3 | 5 | 8 |
| 1998 | 3 | 10 | 13 |
| 1999 | 3 | 8 | 11 |
| 2000 | 3 | 11 | 14 |
| 2001 | 2 | 8 | 10 |
| 2002 | 6 | 8 | 14 |
| 2003 | 3 | 4 | 7 |
| 2004 | 1 | 3 | 4 |
| 2005 | 1 | 4 | 5 |
| 2006 | 1 | 4 | 5 |
| 2007 | 0 | 3 | 3 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 6 | 8 |
| 2010 | 3 | 8 | 11 |
| 2011 | 1 | 0 | 1 |
| 2012 | 3 | 4 | 7 |
| 2013 | 6 | 1 | 7 |
| 2014 | 5 | 4 | 9 |
| 2015 | 2 | 3 | 5 |
| 2016 | 5 | 4 | 9 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 4 | 6 |
| 2019 | 4 | 7 | 11 |
| 2020 | 2 | 4 | 6 |
| 2021 | 4 | 2 | 6 |
| 2022 | 3 | 3 | 6 |
| 2023 | 4 | 1 | 5 |
Below are the most recent publications written about "Glucagon" by people in Profiles.
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An insulin-regulated arrestin domain protein controls hepatic glucagon action. J Biol Chem. 2023 08; 299(8):105045.
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Circulating levels of all proglucagon-derived peptides are differentially regulated postprandially by obesity status and in response to high-fat meals vs. high-carbohydrate meals. Clin Nutr. 2023 08; 42(8):1369-1378.
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Human epicardial adipose tissue expresses glucose-dependent insulinotropic polypeptide, glucagon, and glucagon-like peptide-1 receptors as potential targets of pleiotropic therapies. Eur J Prev Cardiol. 2023 06 01; 30(8):680-693.
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Circulating levels of proglucagon-derived peptides are differentially regulated by the glucagon-like peptide-1 agonist liraglutide and the centrally acting naltrexone/bupropion and can predict future weight loss and metabolic improvements: A 6-month long interventional study. Diabetes Obes Metab. 2023 09; 25(9):2561-2574.
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Circulating levels of gastrointestinal hormones in prediabetes reversing to normoglycemia or progressing to diabetes in a year-A cross-sectional and prospective analysis. Diabetes Res Clin Pract. 2023 May; 199:110636.
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Glucagon receptor antagonists might stimulate ß-cell expansion. Nat Rev Endocrinol. 2022 11; 18(11):659-660.
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Executable models of immune signaling pathways in HIV-associated atherosclerosis. NPJ Syst Biol Appl. 2022 09 21; 8(1):35.
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Circulating levels of five proglucagon-derived peptides in response to intravenous or oral glucose or lipids and to a mixed-meal in subjects with normal weight, overweight, and obesity. Clin Nutr. 2022 09; 41(9):1969-1976.
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A GH Secretagogue Receptor Agonist (LUM-201) Elicits Greater GH Responses than Standard GH Secretagogues in Subjects of a Pediatric GH Deficiency Trial. Horm Res Paediatr. 2022; 95(1):76-81.
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Pramlintide for post-bariatric hypoglycaemia. Diabetes Obes Metab. 2022 06; 24(6):1021-1028.