"Genes, erbB-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
MeSH Number(s)
G05.360.340.024.340.375.500.791.295.300
Concept/Terms
Genes, erbB-1- Genes, erbB-1
- Genes, erbB1
- Gene, erbB1
- erbB1 Gene
- erbB1 Genes
- erbB-1 Genes
- erbB 1 Genes
- erbB-1 Gene
v-erbB Genes- v-erbB Genes
- v erbB Genes
- v-erbB Gene
- v-erbB Oncogenes
- v erbB Oncogenes
- v-erbB Oncogene
c-erbB-1 Genes- c-erbB-1 Genes
- c erbB 1 Genes
- c-erbB-1 Gene
- EGFR Genes
- Epidermal Growth Factor Receptor Genes
- c-erbB-1 Proto-Oncogenes
- c erbB 1 Proto Oncogenes
- c-erbB-1 Proto-Oncogene
- Genes, EGFR
- EGFR Gene
Below are MeSH descriptors whose meaning is more general than "Genes, erbB-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-1".
This graph shows the total number of publications written about "Genes, erbB-1" by people in Harvard Catalyst Profiles by year, and whether "Genes, erbB-1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 2 | 4 |
| 2005 | 4 | 2 | 6 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 6 | 5 | 11 |
| 2009 | 0 | 1 | 1 |
| 2010 | 4 | 3 | 7 |
| 2011 | 4 | 4 | 8 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 4 | 3 | 7 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Genes, erbB-1" by people in Profiles.
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Significance of Polar Charged Amino Acids in Compound Mutations in EGFR-mutated Patients Treated With First-line Afatinib. In Vivo. 2022 Jul-Aug; 36(4):1829-1833.
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Traditional Diagnostics versus Disruptive Technology: The Role of the Pathologist in the Era of Liquid Biopsy. Cancer Res. 2020 08 15; 80(16):3197-3199.
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Factors associated with recurrent leptomeningeal metastases in patients with EGFR-mutated non-small-cell lung cancer. Pol Arch Intern Med. 2019 11 29; 129(11):836-838.
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Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):10025-10030.
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Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants. Nat Commun. 2018 06 18; 9(1):2378.
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Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing. JAMA Oncol. 2018 06 01; 4(6):838-841.
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Predicting epidermal growth factor receptor gene amplification status in glioblastoma multiforme by quantitative enhancement and necrosis features deriving from conventional magnetic resonance imaging. Medicine (Baltimore). 2018 May; 97(21):e10833.
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Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma. Ann Oncol. 2018 03 01; 29(3):700-706.
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Worldwide Frequency of Commonly Detected EGFR Mutations. Arch Pathol Lab Med. 2018 Feb; 142(2):163-167.
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A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations. Clin Cancer Res. 2017 Dec 15; 23(24):7467-7473.