"Genes, bcl-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The B-cell leukemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t(11;14) translocation, which is characteristic of mantle zone-derived B-cell lymphomas. The human c-bcl-1 gene is located at 11q13 on the long arm of chromosome 11.
MeSH Number(s)
G05.360.340.024.340.375.500.791.148
Concept/Terms
Genes, bcl-1- Genes, bcl-1
- Genes, bcl 1
- Genes, PRAD1
- Gene, PRAD1
- PRAD1 Gene
- PRAD1 Genes
- Genes, Cyclin D1
- bcl-1 Genes
- Gene, bcl-1
- bcl 1 Genes
- bcl-1 Gene
- Cyclin D1 Genes
- Cyclin D1 Gene
- Gene, Cyclin D1
c-bcl-1 Genes- c-bcl-1 Genes
- Gene, c-bcl-1
- Genes, c-bcl-1
- c bcl 1 Genes
- c-bcl-1 Gene
- c-bcl-1 Proto-Oncogenes
- Proto-Oncogene, c-bcl-1
- Proto-Oncogenes, c-bcl-1
- c bcl 1 Proto Oncogenes
- c-bcl-1 Proto-Oncogene
Below are MeSH descriptors whose meaning is more general than "Genes, bcl-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, bcl-1".
This graph shows the total number of publications written about "Genes, bcl-1" by people in Harvard Catalyst Profiles by year, and whether "Genes, bcl-1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
Below are the most recent publications written about "Genes, bcl-1" by people in Profiles.
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The transforming growth factor-a and cyclin D1 genes are direct targets of ß-catenin signaling in hepatocyte proliferation. J Hepatol. 2011 Jul; 55(1):86-95.
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Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells. Mol Cell Biol. 2010 Aug; 30(16):4045-59.
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A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases. Clin Cancer Res. 2009 Jul 01; 15(13):4431-8.
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p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor. Cancer Res. 2009 Jan 15; 69(2):440-8.
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Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. J Biol Chem. 2009 Mar 13; 284(11):7157-64.
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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res. 2008 Oct 01; 68(19):7795-802.
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Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science. 2008 Feb 01; 319(5863):627-30.
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The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development. Cancer Res. 2007 Aug 15; 67(16):7613-20.
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Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab. Pharmacogenet Genomics. 2006 Jul; 16(7):475-83.
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Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood. 2006 Sep 01; 108(5):1744-50.