"Genes, Switch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realized) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation.
MeSH Number(s)
G05.360.340.024.340.425.420
Concept/Terms
Switch Complexes- Switch Complexes
- Complexes, Switch
- Switching Complex
- Complex, Switching
- Switching Complexes
- Complexes, Switching
Below are MeSH descriptors whose meaning is more general than "Genes, Switch".
Below are MeSH descriptors whose meaning is more specific than "Genes, Switch".
This graph shows the total number of publications written about "Genes, Switch" by people in Harvard Catalyst Profiles by year, and whether "Genes, Switch" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 2 | 4 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
Below are the most recent publications written about "Genes, Switch" by people in Profiles.
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Theoretical investigation of a genetic switch for metabolic adaptation. PLoS One. 2020; 15(5):e0226453.
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Integrated transcriptomic correlation network analysis identifies COPD molecular determinants. Sci Rep. 2020 02 25; 10(1):3361.
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GemC1 is a critical switch for neural stem cell generation in the postnatal brain. Glia. 2019 12; 67(12):2360-2373.
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Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 07 10; 146(13).
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Caffeine-inducible gene switches controlling experimental diabetes. Nat Commun. 2018 06 19; 9(1):2318.
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Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nat Genet. 2018 02; 50(2):250-258.
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Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies. Br J Haematol. 2018 03; 180(5):630-643.
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Notch signaling: switching an oncogene to a tumor suppressor. Blood. 2014 Apr 17; 123(16):2451-9.
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Developmental biology. Deserts and waves in gene expression. Science. 2013 Jun 07; 340(6137):1181-2.
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Modular development of the teleost trunk along the dorsoventral axis and zic1/zic4 as selector genes in the dorsal module. Development. 2013 Apr; 140(7):1486-96.