Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Genes, BRCA2

"Genes, BRCA2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)


This graph shows the total number of publications written about "Genes, BRCA2" by people in Harvard Catalyst Profiles by year, and whether "Genes, BRCA2" was a major or minor topic of these publication.
Bar chart showing 343 publications over 21 distinct years, with a maximum of 25 publications in 2008 and 2015
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.