Harvard Catalyst Profiles

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Genes, BRCA1

"Genes, BRCA1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 17 at locus 17q21. Mutations of this gene are associated with the formation of familial breast and ovarian cancer. It encodes a large, nuclear protein that is a component of DNA repair pathways.


This graph shows the total number of publications written about "Genes, BRCA1" by people in Harvard Catalyst Profiles by year, and whether "Genes, BRCA1" was a major or minor topic of these publication.
Bar chart showing 468 publications over 26 distinct years, with a maximum of 28 publications in 2005
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.