"Gene Knockout Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.
Concept/Terms
Gene Knockout Techniques- Gene Knockout Techniques
- Gene Knockout Technique
- Knockout Technique, Gene
- Knockout Techniques, Gene
- Technique, Gene Knockout
- Techniques, Gene Knockout
- Gene Knockout
- Gene Knockouts
- Knockout, Gene
- Knockouts, Gene
- Gene Knock-Out Techniques
- Gene Knock-Out Technique
- Knock-Out Technique, Gene
- Knock-Out Techniques, Gene
- Technique, Gene Knock-Out
- Techniques, Gene Knock-Out
- Gene Knock Out
- Gene Knock Outs
- Knock Out, Gene
- Knock Outs, Gene
- Out, Gene Knock
- Outs, Gene Knock
- Gene Knock Out Techniques
Below are MeSH descriptors whose meaning is more general than "Gene Knockout Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knockout Techniques".
This graph shows the total number of publications written about "Gene Knockout Techniques" by people in Harvard Catalyst Profiles by year, and whether "Gene Knockout Techniques" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 5 | 5 |
| 2009 | 2 | 8 | 10 |
| 2010 | 3 | 19 | 22 |
| 2011 | 3 | 29 | 32 |
| 2012 | 3 | 30 | 33 |
| 2013 | 2 | 38 | 40 |
| 2014 | 6 | 30 | 36 |
| 2015 | 3 | 49 | 52 |
| 2016 | 6 | 51 | 57 |
| 2017 | 7 | 40 | 47 |
| 2018 | 2 | 44 | 46 |
| 2019 | 1 | 62 | 63 |
| 2020 | 3 | 37 | 40 |
| 2021 | 1 | 34 | 35 |
| 2022 | 0 | 3 | 3 |
Below are the most recent publications written about "Gene Knockout Techniques" by people in Profiles.
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Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy. Nature. 2022 08; 608(7921):174-180.
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Eukaryotic Initiation Factor 5A2 Regulates Expression of Antiviral Genes. J Mol Biol. 2022 05 30; 434(10):167564.
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Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress. Proc Natl Acad Sci U S A. 2022 01 18; 119(3).
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Hepatitis B and Hepatitis C Virus Infection Promote Liver Fibrogenesis through a TGF-ß1-Induced OCT4/Nanog Pathway. J Immunol. 2022 02 01; 208(3):672-684.
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Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects. Genome Biol. 2021 12 20; 22(1):343.
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Simplified Gene Knockout by CRISPR-Cas9-Induced Homologous Recombination. ACS Synth Biol. 2022 01 21; 11(1):497-501.
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A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer. Nat Commun. 2021 12 08; 12(1):7139.
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Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation. Blood Cancer J. 2021 12 04; 11(12):194.
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Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Nat Genet. 2021 12; 53(12):1664-1672.
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Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. Nat Commun. 2021 11 24; 12(1):6825.