"Galectin 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.
Concept/Terms
Galectin 3- Galectin 3
- CBP-30
- CBP-35
- CBP35
- Epsilon-Binding Protein
- Epsilon Binding Protein
- Galectin-3
- HL-29
- IgE Binding Protein
- Binding Protein, IgE
- Protein, IgE Binding
- IgEBP
- L-29 Lectin
- L 29 Lectin
- L-31
- L-34
- L30 Lectin
- LGALS3
- Mac-2 Antigen
- Antigen, Mac-2
- Mac 2 Antigen
- Macrophage-2 Antigen
- Antigen, Macrophage-2
- Macrophage 2 Antigen
- Carbohydrate-Binding Protein 35
- Carbohydrate Binding Protein 35
Below are MeSH descriptors whose meaning is more general than "Galectin 3".
Below are MeSH descriptors whose meaning is more specific than "Galectin 3".
This graph shows the total number of publications written about "Galectin 3" by people in Harvard Catalyst Profiles by year, and whether "Galectin 3" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 5 | 2 | 7 |
| 2010 | 3 | 1 | 4 |
| 2011 | 2 | 2 | 4 |
| 2012 | 3 | 2 | 5 |
| 2013 | 6 | 0 | 6 |
| 2014 | 8 | 1 | 9 |
| 2015 | 9 | 3 | 12 |
| 2016 | 8 | 6 | 14 |
| 2017 | 2 | 1 | 3 |
| 2018 | 7 | 2 | 9 |
| 2019 | 3 | 3 | 6 |
| 2020 | 3 | 1 | 4 |
| 2021 | 3 | 2 | 5 |
| 2022 | 2 | 0 | 2 |
Below are the most recent publications written about "Galectin 3" by people in Profiles.
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MG-Pe: A Novel Galectin-3 Ligand with Antimelanoma Properties and Adjuvant Effects to Dacarbazine. Int J Mol Sci. 2022 Jul 11; 23(14).
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Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB. Front Immunol. 2022; 13:915890.
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Endogenous galectin-3 is required for skeletal muscle repair. Glycobiology. 2021 11 18; 31(10):1295-1307.
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Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases. Cells. 2021 11 05; 10(11).
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Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension. J Pediatr. 2022 02; 241:68-76.e3.
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Protozoan-Viral-Bacterial Co-Infections Alter Galectin Levels and Associated Immunity Mediators in the Female Genital Tract. Front Cell Infect Microbiol. 2021; 11:649940.
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Role of galectin-3 in the pathogenesis of arrhythmogenic cardiomyopathy-It's complicated. Heart Rhythm. 2021 08; 18(8):1404-1405.
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Golgi a1,2-mannosidase I induces clustering and compartmentalization of CD147 during epithelial cell migration. Cell Adh Migr. 2020 12; 14(1):96-105.
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Time-dependent, dynamic prediction of fatty acid-binding protein 4, Galectin-3, and soluble ST2 measurement with poor outcome after acute stroke. Int J Stroke. 2021 08; 16(6):660-668.
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Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection. PLoS Pathog. 2020 08; 16(8):e1008741.