"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.
MeSH Number(s)
D12.776.543.750.100.017
D12.776.543.750.962.500
Concept/Terms
Frizzled Receptors- Frizzled Receptors
- Receptors, Frizzled
- Frizzled Proteins
- Frizzled Receptor
- Receptor, Frizzled
Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".
Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".
This graph shows the total number of publications written about "Frizzled Receptors" by people in Harvard Catalyst Profiles by year, and whether "Frizzled Receptors" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 5 | 2 | 7 |
| 2007 | 2 | 2 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 3 | 4 |
| 2013 | 3 | 4 | 7 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 2 | 3 |
| 2016 | 3 | 0 | 3 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.
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TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. Elife. 2020 09 14; 9.
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Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects. Hum Genet. 2020 Oct; 139(10):1299-1314.
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Frizzled 4 regulates ventral blood vessel remodeling in the zebrafish retina. Dev Dyn. 2019 12; 248(12):1243-1256.
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Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling. Cell Commun Signal. 2019 09 18; 17(1):120.
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Wnt signaling mediates new nephron formation during zebrafish kidney regeneration. Development. 2019 04 29; 146(8).
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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B. Science. 2018 05 11; 360(6389):664-669.
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Anteroposterior axis patterning by early canonical Wnt signaling during hemichordate development. PLoS Biol. 2018 01; 16(1):e2003698.
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The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Cell Signal. 2017 10; 38:85-96.
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Long-Term, Stochastic Editing of Regenerative Anatomy via Targeting Endogenous Bioelectric Gradients. Biophys J. 2017 May 23; 112(10):2231-2243.
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Clinical implication of Frizzled 2 expression and its association with epithelial-to-mesenchymal transition in hepatocellular carcinoma. Int J Oncol. 2017 May; 50(5):1647-1654.