"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.
MeSH Number(s)
D12.776.543.750.100.017
D12.776.543.750.962.500
Concept/Terms
Frizzled Receptors- Frizzled Receptors
- Receptors, Frizzled
- Frizzled Proteins
- Frizzled Receptor
- Receptor, Frizzled
Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".
Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".
This graph shows the total number of publications written about "Frizzled Receptors" by people in Harvard Catalyst Profiles by year, and whether "Frizzled Receptors" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 5 | 2 | 7 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 3 | 4 |
| 2012 | 1 | 3 | 4 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2020 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.
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Sfrp4 and the Biology of Cortical Bone. Curr Osteoporos Rep. 2022 04; 20(2):153-161.
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miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine. Nat Commun. 2021 06 07; 12(1):3339.
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MITF functions as a tumor suppressor in non-small cell lung cancer beyond the canonically oncogenic role. Aging (Albany NY). 2020 12 03; 13(1):646-674.
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TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. Elife. 2020 09 14; 9.
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Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects. Hum Genet. 2020 Oct; 139(10):1299-1314.
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Novel Frizzled-4 Mutation Is Associated With Familial Exudative Vitreoretinopathy Mimicking Persistent Fetal Vasculature. J Pediatr Ophthalmol Strabismus. 2020 Jan 24; 57:e4-e7.
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Frizzled 4 regulates ventral blood vessel remodeling in the zebrafish retina. Dev Dyn. 2019 12; 248(12):1243-1256.
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Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling. Cell Commun Signal. 2019 09 18; 17(1):120.
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Wnt signaling mediates new nephron formation during zebrafish kidney regeneration. Development. 2019 04 29; 146(8).
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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B. Science. 2018 05 11; 360(6389):664-669.