Flurbiprofen

"Flurbiprofen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.

Descriptor ID

D005480

MeSH Number(s)

D02.241.081.751.700.350

D02.455.426.559.389.185.350

Concept/Terms

Below are MeSH descriptors whose meaning is more general than "Flurbiprofen".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Propionates [D02.241.081.751]
Propionic Acids [D02.241.081.751.700]
Flurbiprofen [D02.241.081.751.700.350]
Hydrocarbons [D02.455]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Aromatic [D02.455.426.559]
Benzene Derivatives [D02.455.426.559.389]
Biphenyl Compounds [D02.455.426.559.389.185]
Flurbiprofen [D02.455.426.559.389.185.350]

Below are MeSH descriptors whose meaning is related to "Flurbiprofen".

Below are MeSH descriptors whose meaning is more specific than "Flurbiprofen".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Flurbiprofen" by people in Harvard Catalyst Profiles by year, and whether "Flurbiprofen" was a major or minor topic of these publication.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 2009 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	1	0	1
2009	1	1	2
2013	2	0	2
2019	0	1	1

Below are the most recent publications written about "Flurbiprofen" by people in Profiles.

Combination of Paclitaxel and R-flurbiprofen loaded PLGA nanoparticles suppresses glioblastoma growth on systemic administration. Int J Pharm. 2020 Mar 30; 578:119076.

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Dual-functional core-shell electrospun mats with precisely controlled release of anti-inflammatory and anti-bacterial agents. Mater Sci Eng C Mater Biol Appl. 2019 Jul; 100:514-522.

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Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves a Tonic Inhibition of the Catalytic Subunit. J Biol Chem. 2016 Dec 02; 291(49):25641-25655.

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Sample size determination in group-sequential clinical trials with two co-primary endpoints. Stat Med. 2014 Jul 30; 33(17):2897-913.

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R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease. Brain Res. 2013 Dec 06; 1541:115-27.

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Combination therapy in a transgenic model of Alzheimer's disease. Exp Neurol. 2013 Dec; 250:228-238.

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Multiple applications of flurbiprofen and chlorhexidine chips in patients with chronic periodontitis: a randomized, double blind, parallel, 2-arms clinical trial. J Clin Periodontol. 2011 Nov; 38(11):1037-43.

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R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. PLoS One. 2010 May 13; 5(5):e10628.

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Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. JAMA. 2009 Dec 16; 302(23):2557-64.

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An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1. Biochemistry. 2009 Nov 24; 48(46):10894-904.

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